MONDAY, Jan. 3, 2022 (HealthDay Information) — For hospitalized COVID-19 sufferers, the presence of metabolic syndrome is related to elevated odds of acute respiratory misery syndrome (ARDS) and mortality, in accordance with a examine revealed on-line Dec. 22 in JAMA Community Open.
Joshua L. Denson, M.D., from the Tulane College Faculty of Medication in New Orleans, and colleagues carried out a multicenter cohort examine to look at whether or not metabolic syndrome is related to an elevated danger for ARDS and dying from COVID-19. Outcomes have been in contrast for sufferers hospitalized with COVID-19 with metabolic syndrome (three or extra of the next: weight problems, prediabetes or diabetes, hypertension, dyslipidemia; 5,069 adults) and controls with out metabolic syndrome (23,971 adults).
The researchers discovered that metabolic syndrome was related to an elevated danger for intensive care unit (ICU) admission, invasive mechanical air flow, ARDS, and mortality (adjusted odds ratios, 1.32, 1.45, 1.36, and 1.19, respectively) and with extended hospital and ICU size of keep (median, 8.0 versus 6.8 days and seven.0 versus 6.4 days, respectively). The danger for ARDS elevated in an additive method with every extra metabolic syndrome criterion (one criterion: 10.4 p.c; two standards: 15.3 p.c; three standards: 19.3 p.c; 4 standards: 24.3 p.c).
“Given the excessive charges of metabolic syndrome, weight problems, and diabetes in the US, one speculation for why the US led the world in COVID-19 instances and deaths could possibly be the excessive prevalence of metabolic syndrome on this inhabitants,” the authors write.
A number of authors disclosed monetary ties to the pharmaceutical business.